Uneven modulation of the annexin 1 system in osteoblast-like cells by dexamethasone

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Impaired Osteoblast Differentiation in Annexin A2- and -A5-Deficient Cells

Annexins are a class of calcium-binding proteins with diverse functions in the regulation of lipid rafts, inflammation, fibrinolysis, transcriptional programming and ion transport. Within bone, they are well-characterized as components of mineralizing matrix vesicles, although little else is known as to their function during osteogenesis. We employed shRNA to generate annexin A2 (AnxA2)- or ann...

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ژورنال

عنوان ژورنال: Biochemical and Biophysical Research Communications

سال: 2007

ISSN: 0006-291X

DOI: 10.1016/j.bbrc.2006.12.224